Discovery of a Selective, Substrate-competitive Inhibitor of the Lysine Methyltransferase SETD8. Read more about Discovery of a Selective, Substrate-competitive Inhibitor of the Lysine Methyltransferase SETD8.
Corrigendum: Dual kinase-bromodomain inhibitors for rationally designed polypharmacology. Read more about Corrigendum: Dual kinase-bromodomain inhibitors for rationally designed polypharmacology.
A Methylation-Phosphorylation Switch Determines Sox2 Stability and Function in ESC Maintenance or Differentiation. Read more about A Methylation-Phosphorylation Switch Determines Sox2 Stability and Function in ESC Maintenance or Differentiation.
Lysine methylation-dependent binding of 53BP1 to the pRb tumor suppressor. Read more about Lysine methylation-dependent binding of 53BP1 to the pRb tumor suppressor.
What is the future of bromodomains in targeted drug development? Read more about What is the future of bromodomains in targeted drug development?
Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching. Read more about Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching.
Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants. Read more about Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants.
Recently targeted kinases and their inhibitors-the path to clinical trials. Read more about Recently targeted kinases and their inhibitors-the path to clinical trials.
Lost but making progress-Where will new analgesic drugs come from? Read more about Lost but making progress-Where will new analgesic drugs come from?
Functional Characterization and Categorization of Missense Mutations that Cause Methylmalonyl-CoA Mutase (MUT) Deficiency. Read more about Functional Characterization and Categorization of Missense Mutations that Cause Methylmalonyl-CoA Mutase (MUT) Deficiency.
