Salvage or recovery of failed targets by in situ proteolysis. Read more about Salvage or recovery of failed targets by in situ proteolysis.
Case study--structural genomics and human protein kinases. Read more about Case study--structural genomics and human protein kinases.
A Basic Post-SET Extension of NSDs Is Essential for Nucleosome Binding In Vitro. Read more about A Basic Post-SET Extension of NSDs Is Essential for Nucleosome Binding In Vitro.
Crystal Structures of Human RNA Demethylase Alkbh5 Reveal Basis for Substrate Recognition. Read more about Crystal Structures of Human RNA Demethylase Alkbh5 Reveal Basis for Substrate Recognition.
Benzoselenadiazole-based responsive long-lifetime photoluminescent probes for protein kinases. Read more about Benzoselenadiazole-based responsive long-lifetime photoluminescent probes for protein kinases.
Trimethylation of Histone H3 Lysine 36 by Human Methyltransferase PRDM9. Read more about Trimethylation of Histone H3 Lysine 36 by Human Methyltransferase PRDM9.
Structural and biochemical characterisation of the KLHL3-WNK kinase interaction important in blood pressure regulation. Read more about Structural and biochemical characterisation of the KLHL3-WNK kinase interaction important in blood pressure regulation.
Protein ISGylation delays but does not overcome coronavirus proliferation in a model of fulminant hepatitis. Read more about Protein ISGylation delays but does not overcome coronavirus proliferation in a model of fulminant hepatitis.
Novel approaches for targeting kinases: allosteric inhibition, allosteric activation and pseudokinases. Read more about Novel approaches for targeting kinases: allosteric inhibition, allosteric activation and pseudokinases.
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy. Read more about Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.
