Structure-activity relationship studies of SETD8 inhibitors. Read more about Structure-activity relationship studies of SETD8 inhibitors.
A small molecule targeting ALK1 prevents Notch cooperativity and inhibits functional angiogenesis. Read more about A small molecule targeting ALK1 prevents Notch cooperativity and inhibits functional angiogenesis.
Lysine Demethylase KDM4A Associates with Translation Machinery and Regulates Protein Synthesis. Read more about Lysine Demethylase KDM4A Associates with Translation Machinery and Regulates Protein Synthesis.
Identification of a Fragment-like Small Molecule Ligand for the Methyl-lysine Binding Protein, 53BP1. Read more about Identification of a Fragment-like Small Molecule Ligand for the Methyl-lysine Binding Protein, 53BP1.
Bisubstrate Inhibitor Approach for Targeting Mitotic Kinase Haspin. Read more about Bisubstrate Inhibitor Approach for Targeting Mitotic Kinase Haspin.
Clinical Utility Gene Card for: Fibrodysplasia ossificans progressiva. Read more about Clinical Utility Gene Card for: Fibrodysplasia ossificans progressiva.
Human prostaglandin reductase 1 (PGR1): Substrate specificity, inhibitor analysis and site-directed mutagenesis. Read more about Human prostaglandin reductase 1 (PGR1): Substrate specificity, inhibitor analysis and site-directed mutagenesis.
Identification of Structure-Activity Relationships from Screening a Structurally Compact DNA-Encoded Chemical Library. Read more about Identification of Structure-Activity Relationships from Screening a Structurally Compact DNA-Encoded Chemical Library.
Structural Insights into the Auto-regulation and Cooperativity of the Human Transcription Factor Ets-2. Read more about Structural Insights into the Auto-regulation and Cooperativity of the Human Transcription Factor Ets-2.
The 9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain. Read more about The 9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain.
