Recently targeted kinases and their inhibitors-the path to clinical trials. Read more about Recently targeted kinases and their inhibitors-the path to clinical trials.
Lost but making progress-Where will new analgesic drugs come from? Read more about Lost but making progress-Where will new analgesic drugs come from?
Functional Characterization and Categorization of Missense Mutations that Cause Methylmalonyl-CoA Mutase (MUT) Deficiency. Read more about Functional Characterization and Categorization of Missense Mutations that Cause Methylmalonyl-CoA Mutase (MUT) Deficiency.
ACVR1 Mutations in DIPG: Lessons Learned from FOP. Read more about ACVR1 Mutations in DIPG: Lessons Learned from FOP.
(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells. Read more about (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells.
The Crystal Structure of the RhoA : AKAP-Lbc DH-PH Domain Complex. Read more about The Crystal Structure of the RhoA : AKAP-Lbc DH-PH Domain Complex.
A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics. Read more about A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics.
Identification and structure-function analysis of sub-family selective G protein-coupled receptor kinase inhibitors. Read more about Identification and structure-function analysis of sub-family selective G protein-coupled receptor kinase inhibitors.
Structural basis for selective binding of m(6)A RNA by the YTHDC1 YTH domain. Read more about Structural basis for selective binding of m(6)A RNA by the YTHDC1 YTH domain.
OOMMPPAA: A tool to aid directed synthesis by the combined analysis of activity and structural data. Read more about OOMMPPAA: A tool to aid directed synthesis by the combined analysis of activity and structural data.
