Structural diversity of the epigenetics pocketome. Read more about Structural diversity of the epigenetics pocketome.
Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF. Read more about Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.
Designing selective inhibitors for calcium-dependent protein kinases in apicomplexans. Read more about Designing selective inhibitors for calcium-dependent protein kinases in apicomplexans.
Kinetic characterization of human histone H3 lysine 36 methyltransferases, ASH1L and SETD2. Read more about Kinetic characterization of human histone H3 lysine 36 methyltransferases, ASH1L and SETD2.
Structural Basis of KEAP1 Interactions with Nrf2. Read more about Structural Basis of KEAP1 Interactions with Nrf2.
Pim Kinase Inhibitors Evaluated with a Single-Molecule Engineered Nanopore Sensor. Read more about Pim Kinase Inhibitors Evaluated with a Single-Molecule Engineered Nanopore Sensor.
Tankyrase 1 Inhibitors with Drug-like Properties Identified by Screening a DNA-Encoded Chemical Library. Read more about Tankyrase 1 Inhibitors with Drug-like Properties Identified by Screening a DNA-Encoded Chemical Library.
MemProtMD: Automated Insertion of Membrane Protein Structures into Explicit Lipid Membranes. Read more about MemProtMD: Automated Insertion of Membrane Protein Structures into Explicit Lipid Membranes.
Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2. Read more about Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2.
Mechanisms underlying clinical efficacy of Angiotensin II type 2 receptor (AT2R) antagonist EMA401 in neuropathic pain: clinical tissue and in vitro studies. Read more about Mechanisms underlying clinical efficacy of Angiotensin II type 2 receptor (AT2R) antagonist EMA401 in neuropathic pain: clinical tissue and in vitro studies.
