Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching. Read more about Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching.
Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants. Read more about Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants.
Recently targeted kinases and their inhibitors-the path to clinical trials. Read more about Recently targeted kinases and their inhibitors-the path to clinical trials.
Lost but making progress-Where will new analgesic drugs come from? Read more about Lost but making progress-Where will new analgesic drugs come from?
Functional Characterization and Categorization of Missense Mutations that Cause Methylmalonyl-CoA Mutase (MUT) Deficiency. Read more about Functional Characterization and Categorization of Missense Mutations that Cause Methylmalonyl-CoA Mutase (MUT) Deficiency.
ACVR1 Mutations in DIPG: Lessons Learned from FOP. Read more about ACVR1 Mutations in DIPG: Lessons Learned from FOP.
(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells. Read more about (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells.
The Crystal Structure of the RhoA : AKAP-Lbc DH-PH Domain Complex. Read more about The Crystal Structure of the RhoA : AKAP-Lbc DH-PH Domain Complex.
A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics. Read more about A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics.
Identification and structure-function analysis of sub-family selective G protein-coupled receptor kinase inhibitors. Read more about Identification and structure-function analysis of sub-family selective G protein-coupled receptor kinase inhibitors.
