Bisubstrate Inhibitor Approach for Targeting Mitotic Kinase Haspin. Read more about Bisubstrate Inhibitor Approach for Targeting Mitotic Kinase Haspin.
Clinical Utility Gene Card for: Fibrodysplasia ossificans progressiva. Read more about Clinical Utility Gene Card for: Fibrodysplasia ossificans progressiva.
Human prostaglandin reductase 1 (PGR1): Substrate specificity, inhibitor analysis and site-directed mutagenesis. Read more about Human prostaglandin reductase 1 (PGR1): Substrate specificity, inhibitor analysis and site-directed mutagenesis.
Identification of Structure-Activity Relationships from Screening a Structurally Compact DNA-Encoded Chemical Library. Read more about Identification of Structure-Activity Relationships from Screening a Structurally Compact DNA-Encoded Chemical Library.
Structural Insights into the Auto-regulation and Cooperativity of the Human Transcription Factor Ets-2. Read more about Structural Insights into the Auto-regulation and Cooperativity of the Human Transcription Factor Ets-2.
The 9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain. Read more about The 9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain.
Building a roadmap for developing combination therapies for Alzheimer's disease. Read more about Building a roadmap for developing combination therapies for Alzheimer's disease.
Structure Enabled Design of BAZ2-ICR, A Chemical Probe Targeting the Bromodomains of BAZ2A and BAZ2B. Read more about Structure Enabled Design of BAZ2-ICR, A Chemical Probe Targeting the Bromodomains of BAZ2A and BAZ2B.
Preclinical target validation using patient-derived cells. Read more about Preclinical target validation using patient-derived cells.
A Potent, Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 3 (PRMT3). Read more about A Potent, Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 3 (PRMT3).
