Perspective on Computational and Structural Aspects of Kinase Discovery from IPK2014. Read more about Perspective on Computational and Structural Aspects of Kinase Discovery from IPK2014.
LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor. Read more about LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor.
Structures of the Ets Domains of Transcription Factors ETV1, ETV4, ETV5 and FEV: Determinants of DNA Binding and Redox Regulation by Disulfide bond formation. Read more about Structures of the Ets Domains of Transcription Factors ETV1, ETV4, ETV5 and FEV: Determinants of DNA Binding and Redox Regulation by Disulfide bond formation.
Discovery of a Dual PRMT5-PRMT7 Inhibitor. Read more about Discovery of a Dual PRMT5-PRMT7 Inhibitor.
Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes. Read more about Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes.
Solution-state NMR structure of the putative morphogene protein BolA (PFE0790c) from Plasmodium falciparum. Read more about Solution-state NMR structure of the putative morphogene protein BolA (PFE0790c) from Plasmodium falciparum.
Structural diversity of the epigenetics pocketome. Read more about Structural diversity of the epigenetics pocketome.
Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF. Read more about Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.
Designing selective inhibitors for calcium-dependent protein kinases in apicomplexans. Read more about Designing selective inhibitors for calcium-dependent protein kinases in apicomplexans.
Kinetic characterization of human histone H3 lysine 36 methyltransferases, ASH1L and SETD2. Read more about Kinetic characterization of human histone H3 lysine 36 methyltransferases, ASH1L and SETD2.
