Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1. Read more about Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1.
SPOTing Acetyl-Lysine Dependent Interactions. Read more about SPOTing Acetyl-Lysine Dependent Interactions.
Advantages and pitfalls of an extended gene panel for investigating complex neurometabolic phenotypes. Read more about Advantages and pitfalls of an extended gene panel for investigating complex neurometabolic phenotypes.
Discovery and optimization of a selective ligand for the Switch/Sucrose Non-Fermenting-related bromodomains of Polybromo protein-1 by the use of virtual screening and hydration analysis. Read more about Discovery and optimization of a selective ligand for the Switch/Sucrose Non-Fermenting-related bromodomains of Polybromo protein-1 by the use of virtual screening and hydration analysis.
The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Read more about The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway.
Development of Selective CBP/P300 Benzoxazepine Bromodomain Inhibitors. Read more about Development of Selective CBP/P300 Benzoxazepine Bromodomain Inhibitors.
Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization. Read more about Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization.
Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia. Read more about Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.
Discovery of Potent Pantothenamide Inhibitors of Staphylococcus aureus Pantothenate Kinase through a Minimal SAR Study: Inhibition Is Due to Trapping of the Product. Read more about Discovery of Potent Pantothenamide Inhibitors of Staphylococcus aureus Pantothenate Kinase through a Minimal SAR Study: Inhibition Is Due to Trapping of the Product.
