Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16. Read more about Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16.
Design of a Biased Potent Small Molecule Inhibitor of the Bromodomain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies. Read more about Design of a Biased Potent Small Molecule Inhibitor of the Bromodomain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies.
Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma. Read more about Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma.
Chemical Probes Targeting Epigenetic Proteins: Applications Beyond Oncology. Read more about Chemical Probes Targeting Epigenetic Proteins: Applications Beyond Oncology.
Molecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2. Read more about Molecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2.
Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5. Read more about Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5.
The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity. Read more about The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity.
Development of potent, selective SRPK1 inhibitors as potential topical therapeutics for neovascular eye disease. Read more about Development of potent, selective SRPK1 inhibitors as potential topical therapeutics for neovascular eye disease.
Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase. Read more about Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase.
