Cardiac myosin light chain is phosphorylated by Ca2+/calmodulin-dependent and -independent kinase activities. Read more about Cardiac myosin light chain is phosphorylated by Ca2+/calmodulin-dependent and -independent kinase activities.
LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor. Read more about LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor.
Exploring the role of water in molecular recognition: predicting protein ligandability using a combinatorial search of surface hydration sites. Read more about Exploring the role of water in molecular recognition: predicting protein ligandability using a combinatorial search of surface hydration sites.
Advances and challenges in understanding histone demethylase biology. Read more about Advances and challenges in understanding histone demethylase biology.
Identification of small molecule inhibitors that block the Toxoplasma gondii rhoptry kinase ROP18. Read more about Identification of small molecule inhibitors that block the Toxoplasma gondii rhoptry kinase ROP18.
H3K27me3 demethylases regulate in vitro chondrogenesis and chondrocyte activity in osteoarthritis. Read more about H3K27me3 demethylases regulate in vitro chondrogenesis and chondrocyte activity in osteoarthritis.
Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening. Read more about Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening.
High resolution crystal structure of DPF3b in complex with an acetylated histone peptide. Read more about High resolution crystal structure of DPF3b in complex with an acetylated histone peptide.
Effect of BET Missense Mutations on Bromodomain Function, Inhibitor Binding and Stability. Read more about Effect of BET Missense Mutations on Bromodomain Function, Inhibitor Binding and Stability.
Chemical Biology Approaches for Characterization of Epigenetic Regulators. Read more about Chemical Biology Approaches for Characterization of Epigenetic Regulators.