Discovery of a PCAF Bromodomain Chemical Probe. Read more about Discovery of a PCAF Bromodomain Chemical Probe.
BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells. Read more about BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells.
CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation. Read more about CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation.
Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2). Read more about Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2).
Turning a Substrate Peptide into a Potent Inhibitor for the Histone Methyltransferase SETD8. Read more about Turning a Substrate Peptide into a Potent Inhibitor for the Histone Methyltransferase SETD8.
Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening. Read more about Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening.
Identification of CLK1 Inhibitors by a Fragment-linking Based Virtual Screening. Read more about Identification of CLK1 Inhibitors by a Fragment-linking Based Virtual Screening.
Predictions of ligand selectivity from absolute binding free energy calculations. Read more about Predictions of ligand selectivity from absolute binding free energy calculations.
Early-life antibiotic treatment enhances the pathogenicity of CD4+ T cells during intestinal inflammation. Read more about Early-life antibiotic treatment enhances the pathogenicity of CD4+ T cells during intestinal inflammation.
Functions of bromodomain-containing proteins and their roles in homeostasis and cancer. Read more about Functions of bromodomain-containing proteins and their roles in homeostasis and cancer.
