Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair. Read more about Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair.
Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24. Read more about Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24.
Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly. Read more about Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.
Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin. Read more about Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin.
Functional and structural characterization of a novel putative cysteine protease cell wall-modifying multi-domain enzyme selected from a microbial metagenome. Read more about Functional and structural characterization of a novel putative cysteine protease cell wall-modifying multi-domain enzyme selected from a microbial metagenome.
Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors. Read more about Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.
Discovery of a PCAF Bromodomain Chemical Probe. Read more about Discovery of a PCAF Bromodomain Chemical Probe.
BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells. Read more about BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells.
CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation. Read more about CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation.
Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2). Read more about Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2).