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Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair.

  • Read more about Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair.

Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24.

  • Read more about Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24.

Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.

  • Read more about Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.

Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin.

  • Read more about Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin.

Functional and structural characterization of a novel putative cysteine protease cell wall-modifying multi-domain enzyme selected from a microbial metagenome.

  • Read more about Functional and structural characterization of a novel putative cysteine protease cell wall-modifying multi-domain enzyme selected from a microbial metagenome.

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.

  • Read more about Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.

Discovery of a PCAF Bromodomain Chemical Probe.

  • Read more about Discovery of a PCAF Bromodomain Chemical Probe.

BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells.

  • Read more about BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells.

CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation.

  • Read more about CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation.

Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2).

  • Read more about Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2).

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