Gentle, fast and effective crystal soaking by acoustic dispensing. Read more about Gentle, fast and effective crystal soaking by acoustic dispensing.
Proper modelling of ligand binding requires an ensemble of bound and unbound states. Read more about Proper modelling of ligand binding requires an ensemble of bound and unbound states.
The XChemExplorer graphical workflow tool for routine or large-scale protein-ligand structure determination. Read more about The XChemExplorer graphical workflow tool for routine or large-scale protein-ligand structure determination.
WONKA and OOMMPPAA: analysis of protein-ligand interaction data to direct structure-based drug design. Read more about WONKA and OOMMPPAA: analysis of protein-ligand interaction data to direct structure-based drug design.
Development of a monoclonal anti-ADAMTS-5 antibody that specifically blocks the interaction with LRP1. Read more about Development of a monoclonal anti-ADAMTS-5 antibody that specifically blocks the interaction with LRP1.
Tetrahydroisoquinoline-7-carboxamide Derivatives as New Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors. Read more about Tetrahydroisoquinoline-7-carboxamide Derivatives as New Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors.
Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family. Read more about Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.
Partial-occupancy binders identified by the Pan-Dataset Density Analysis method offer new chemical opportunities and reveal cryptic binding sites. Read more about Partial-occupancy binders identified by the Pan-Dataset Density Analysis method offer new chemical opportunities and reveal cryptic binding sites.
Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation. Read more about Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation.
MOB1 mediated phospho-recognition in the core mammalian Hippo pathway. Read more about MOB1 mediated phospho-recognition in the core mammalian Hippo pathway.
