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An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells.

  • Read more about An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells.

Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.

  • Read more about Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.

Activation loop targeting strategy for design of receptor-interacting protein kinase 2 (RIPK2) inhibitors.

  • Read more about Activation loop targeting strategy for design of receptor-interacting protein kinase 2 (RIPK2) inhibitors.

CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function.

  • Read more about CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function.

Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry.

  • Read more about Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry.

Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63.

  • Read more about Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63.

Creation of a novel class of potent and selective MutT Homolog 1 (MTH1) inhibitors using fragment-based screening and structure-based drug design.

  • Read more about Creation of a novel class of potent and selective MutT Homolog 1 (MTH1) inhibitors using fragment-based screening and structure-based drug design.

Structural and histone binding studies of the chromo barrel domain of TIP60.

  • Read more about Structural and histone binding studies of the chromo barrel domain of TIP60.

Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation.

  • Read more about Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation.

New opportunities for kinase drug repurposing and target discovery.

  • Read more about New opportunities for kinase drug repurposing and target discovery.

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