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Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.

  • Read more about Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.

Identifying small molecule binding sites for epigenetic proteins at domain-domain interfaces.

  • Read more about Identifying small molecule binding sites for epigenetic proteins at domain-domain interfaces.

Halogen-aromatic π-interactions modulate inhibitor residence time.

  • Read more about Halogen-aromatic π-interactions modulate inhibitor residence time.

A Pseudo-Kinase Double Act.

  • Read more about A Pseudo-Kinase Double Act.

Proteostasis in Huntington's disease: disease mechanisms and therapeutic opportunities.

  • Read more about Proteostasis in Huntington's disease: disease mechanisms and therapeutic opportunities.

Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.

  • Read more about Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.

A novel INS mutation in a family with MODY: variable insulin secretion and putative mechanisms.

  • Read more about A novel INS mutation in a family with MODY: variable insulin secretion and putative mechanisms.

Discovery of Ubiquitin Deamidases in the Pathogenic Arsenal of Legionella pneumophila.

  • Read more about Discovery of Ubiquitin Deamidases in the Pathogenic Arsenal of Legionella pneumophila.

Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases.

  • Read more about Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases.

Donated chemical probes for open science.

  • Read more about Donated chemical probes for open science.

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