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Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer.

  • Read more about Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer.

Global analysis of protein folding using massively parallel design, synthesis, and testing.

  • Read more about Global analysis of protein folding using massively parallel design, synthesis, and testing.

NEK1 kinase domain structure and its dynamic protein interactome after exposure to Cisplatin.

  • Read more about NEK1 kinase domain structure and its dynamic protein interactome after exposure to Cisplatin.

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

  • Read more about ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

Design of a chemical probe for the Bromodomain and Plant Homeodomain Finger-containing (BRPF) family of proteins.

  • Read more about Design of a chemical probe for the Bromodomain and Plant Homeodomain Finger-containing (BRPF) family of proteins.

BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis.

  • Read more about BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis.

IDUA mutational profile and genotype-phenotype relationships in UK patients with Mucopolysaccharidosis I.

  • Read more about IDUA mutational profile and genotype-phenotype relationships in UK patients with Mucopolysaccharidosis I.

(19) F NMR isotropic chemical shift for efficient screening of fluorinated fragments which are racemates and/or display multiple conformers.

  • Read more about (19) F NMR isotropic chemical shift for efficient screening of fluorinated fragments which are racemates and/or display multiple conformers.

Progress towards a public chemogenomic set for protein kinases and a call for contributions.

  • Read more about Progress towards a public chemogenomic set for protein kinases and a call for contributions.

A statistical analysis on the performance of MMPBSA versus absolute binding free energy calculations: bromodomains as a case study.

  • Read more about A statistical analysis on the performance of MMPBSA versus absolute binding free energy calculations: bromodomains as a case study.

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