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A Pseudo-Kinase Double Act.

  • Read more about A Pseudo-Kinase Double Act.

A structure-based approach towards identification of inhibitory fragments for eleven-nineteen-leukemia protein (ENL).

  • Read more about A structure-based approach towards identification of inhibitory fragments for eleven-nineteen-leukemia protein (ENL).

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

  • Read more about MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2.

  • Read more about An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2.

Selective inhibitors of a human prolyl hydroxylase (OGFOD1) involved in ribosomal decoding.

  • Read more about Selective inhibitors of a human prolyl hydroxylase (OGFOD1) involved in ribosomal decoding.

Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.

  • Read more about Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.

Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.

  • Read more about Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.

Allosteric Modulation of Binding Specificity by Alternative Packing of Protein Cores.

  • Read more about Allosteric Modulation of Binding Specificity by Alternative Packing of Protein Cores.

Arginine does not rescue p.Q188R mutation deleterious effect in classic galactosemia.

  • Read more about Arginine does not rescue p.Q188R mutation deleterious effect in classic galactosemia.

Guiding COMPASS: Dpy-30 Positions SET1/MLL Epigenetic Signaling.

  • Read more about Guiding COMPASS: Dpy-30 Positions SET1/MLL Epigenetic Signaling.

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