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Structural and functional consequences of the STAT5BN642H driver mutation.

  • Read more about Structural and functional consequences of the STAT5BN642H driver mutation.

Expanding the genetic and phenotypic spectrum of branched-chain amino acid transferase 2 deficiency.

  • Read more about Expanding the genetic and phenotypic spectrum of branched-chain amino acid transferase 2 deficiency.

A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin.

  • Read more about A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin.

Insights into the full-length SRPK2 structure and its hydrodynamic behavior.

  • Read more about Insights into the full-length SRPK2 structure and its hydrodynamic behavior.

Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition.

  • Read more about Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition.

Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation.

  • Read more about Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation.

Streamlining the production of proteins for structural biology.

  • Read more about Streamlining the production of proteins for structural biology.

A genetics-led approach defines the drug target landscape of 30 immune-related traits.

  • Read more about A genetics-led approach defines the drug target landscape of 30 immune-related traits.

Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1).

  • Read more about Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1).

CDK16: the pick of the understudied PCTAIRE kinases.

  • Read more about CDK16: the pick of the understudied PCTAIRE kinases.

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