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A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain.

  • Read more about A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain.

Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities.

  • Read more about Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities.

NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.

  • Read more about NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.

A Bench-Stable Transfer Reagent for the Synthesis of Trifluoromethyl-sulfonimidamides from Sulfinamides.

  • Read more about A Bench-Stable Transfer Reagent for the Synthesis of Trifluoromethyl-sulfonimidamides from Sulfinamides.

New tools for evaluating protein tyrosine sulphation: Tyrosyl Protein Sulphotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors.

  • Read more about New tools for evaluating protein tyrosine sulphation: Tyrosyl Protein Sulphotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors.

New tools for carbohydrate sulphation analysis: Heparan Sulphate 2- O -sulphotransferase (HS2ST) is a target for small molecule protein kinase inhibitors.

  • Read more about New tools for carbohydrate sulphation analysis: Heparan Sulphate 2- O -sulphotransferase (HS2ST) is a target for small molecule protein kinase inhibitors.

Identification of Rpl29 as a major substrate of the lysine methyltransferase Set7/9.

  • Read more about Identification of Rpl29 as a major substrate of the lysine methyltransferase Set7/9.

SATurn: A modular bioinformatics framework for the design of robust maintainable web-based and standalone applications.

  • Read more about SATurn: A modular bioinformatics framework for the design of robust maintainable web-based and standalone applications.

A TFEB nuclear export signal integrates amino acid supply and glucose availability.

  • Read more about A TFEB nuclear export signal integrates amino acid supply and glucose availability.

Chemoproteomics and Chemical Probes for Target Discovery.

  • Read more about Chemoproteomics and Chemical Probes for Target Discovery.

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