Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity. Read more about Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity.
A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels. Read more about A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels.
Organizational innovation for developing new medicines that target aging and age-related conditions. Read more about Organizational innovation for developing new medicines that target aging and age-related conditions.
RNA interference may result in unexpected phenotypes in Caenorhabditis elegans. Read more about RNA interference may result in unexpected phenotypes in Caenorhabditis elegans.
Design and characterization of mutant and wild-type huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems. Read more about Design and characterization of mutant and wild-type huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems.
Role of protein structure in variant annotation: structural insight of mutations causing 6-pyruvoyl-tetrahydropterin synthase deficiency. Read more about Role of protein structure in variant annotation: structural insight of mutations causing 6-pyruvoyl-tetrahydropterin synthase deficiency.
Solution structures and biophysical analysis of full-length group A PAKs reveal they are monomeric and auto-inhibited in cis. Read more about Solution structures and biophysical analysis of full-length group A PAKs reveal they are monomeric and auto-inhibited in cis.
Divergent roles of prostacyclin and PGE2 in human tendinopathy. Read more about Divergent roles of prostacyclin and PGE2 in human tendinopathy.
Targeting the Small GTPase Superfamily through their Regulatory Proteins. Read more about Targeting the Small GTPase Superfamily through their Regulatory Proteins.
4'-Phosphopantetheine and long acyl chain-dependent interactions are integral to human mitochondrial acyl carrier protein function. Read more about 4'-Phosphopantetheine and long acyl chain-dependent interactions are integral to human mitochondrial acyl carrier protein function.
