Modular Synthesis of Di- and Tri-substituted Imidazoles from Ketones and Aldehydes: A Route to Kinase Inhibitors. Read more about Modular Synthesis of Di- and Tri-substituted Imidazoles from Ketones and Aldehydes: A Route to Kinase Inhibitors.
The natural history of infantile mitochondrial DNA depletion syndrome due to RRM2B deficiency. Read more about The natural history of infantile mitochondrial DNA depletion syndrome due to RRM2B deficiency.
Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target. Read more about Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target.
The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K. Read more about The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
LYAR potentiates rRNA synthesis by recruiting BRD2/4 and the MYST-type acetyltransferase KAT7 to rDNA. Read more about LYAR potentiates rRNA synthesis by recruiting BRD2/4 and the MYST-type acetyltransferase KAT7 to rDNA.
Development of Pyridine-based Inhibitors for the Human Vaccinia-related Kinases 1 and 2. Read more about Development of Pyridine-based Inhibitors for the Human Vaccinia-related Kinases 1 and 2.
A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function. Read more about A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.
Fostering open collaboration in drug development for paediatric brain tumours. Read more about Fostering open collaboration in drug development for paediatric brain tumours.
SETD7 at the heart of chromatin factor interplay. Read more about SETD7 at the heart of chromatin factor interplay.
Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation. Read more about Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation.
