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Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition.

  • Read more about Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition.

Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation.

  • Read more about Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation.

Streamlining the production of proteins for structural biology.

  • Read more about Streamlining the production of proteins for structural biology.

A genetics-led approach defines the drug target landscape of 30 immune-related traits.

  • Read more about A genetics-led approach defines the drug target landscape of 30 immune-related traits.

Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1).

  • Read more about Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1).

CDK16: the pick of the understudied PCTAIRE kinases.

  • Read more about CDK16: the pick of the understudied PCTAIRE kinases.

High-Throughput Purification of Protein Kinases from Escherichia coli and Insect Cells.

  • Read more about High-Throughput Purification of Protein Kinases from Escherichia coli and Insect Cells.

High-Throughput Site-Directed Mutagenesis.

  • Read more about High-Throughput Site-Directed Mutagenesis.

Target 2035: probing the human proteome.

  • Read more about Target 2035: probing the human proteome.

Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase.

  • Read more about Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase.

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