Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene. Read more about Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene.
Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking. Read more about Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking.
Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK. Read more about Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK.
Identification of lysine isobutyrylation as a new histone modification mark. Read more about Identification of lysine isobutyrylation as a new histone modification mark.
How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition-The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine. Read more about How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition-The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine.
Human MettL3-MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro. Read more about Human MettL3-MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro.
Molecular basis for ubiquitin ligase CRL2FEM1C-mediated recognition of C-degron. Read more about Molecular basis for ubiquitin ligase CRL2FEM1C-mediated recognition of C-degron.
The low-cost Shifter microscope stage transforms the speed and robustness of protein crystal harvesting. Read more about The low-cost Shifter microscope stage transforms the speed and robustness of protein crystal harvesting.
A High-Throughput RNA Displacement Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex toward Developing Therapeutics for COVID-19. Read more about A High-Throughput RNA Displacement Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex toward Developing Therapeutics for COVID-19.
The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification. Read more about The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification.
