STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers. Read more about STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers.
Structural Basis for the Binding Selectivity of Human CDY Chromodomains. Read more about Structural Basis for the Binding Selectivity of Human CDY Chromodomains.
Quantifying CDK inhibitor selectivity in live cells. Read more about Quantifying CDK inhibitor selectivity in live cells.
Human aminolevulinate synthase structure reveals a eukaryotic-specific autoinhibitory loop regulating substrate binding and product release. Read more about Human aminolevulinate synthase structure reveals a eukaryotic-specific autoinhibitory loop regulating substrate binding and product release.
A lower X-gate in TASK channels traps inhibitors within the vestibule. Read more about A lower X-gate in TASK channels traps inhibitors within the vestibule.
Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold. Read more about Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold.
Recognition of nonproline N-terminal residues by the Pro/N-degron pathway. Read more about Recognition of nonproline N-terminal residues by the Pro/N-degron pathway.
Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution. Read more about Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution.
Backbone resonance assignments of the catalytic and regulatory domains of Ca2+/calmodulin-dependent protein kinase 1D. Read more about Backbone resonance assignments of the catalytic and regulatory domains of Ca2+/calmodulin-dependent protein kinase 1D.
Epigenetic switch-induced viral mimicry evasion in chemotherapy resistant breast cancer. Read more about Epigenetic switch-induced viral mimicry evasion in chemotherapy resistant breast cancer.
