Selective targeting of the αC and DFG-out pocket in p38 MAPK. Read more about Selective targeting of the αC and DFG-out pocket in p38 MAPK.
A novel allosteric modulator of the cannabinoid CB1 receptor ameliorates hyperdopaminergia endophenotypes in rodent models. Read more about A novel allosteric modulator of the cannabinoid CB1 receptor ameliorates hyperdopaminergia endophenotypes in rodent models.
Design of new disubstituted imidazo[1,2-b]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation. Read more about Design of new disubstituted imidazo[1,2-b]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation.
Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major. Read more about Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major.
Discovery of novel immunopharmacological ligands targeting the IL-17 inflammatory pathway. Read more about Discovery of novel immunopharmacological ligands targeting the IL-17 inflammatory pathway.
Epigenetics 2.0: Special Issue on Epigenetics-Call for Papers. Read more about Epigenetics 2.0: Special Issue on Epigenetics-Call for Papers.
SARS-CoV-2 antibody prevalence, titres and neutralising activity in an antenatal cohort, United Kingdom, 14 April to 15 June 2020. Read more about SARS-CoV-2 antibody prevalence, titres and neutralising activity in an antenatal cohort, United Kingdom, 14 April to 15 June 2020.
RecQ helicases in DNA repair and cancer targets. Read more about RecQ helicases in DNA repair and cancer targets.
Chemical Starting Matter for HNF4α Ligand Discovery and Chemogenomics. Read more about Chemical Starting Matter for HNF4α Ligand Discovery and Chemogenomics.
Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3. Read more about Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3.
