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Mining Public Domain Data to Develop Selective DYRK1A Inhibitors.

  • Read more about Mining Public Domain Data to Develop Selective DYRK1A Inhibitors.

Inhibition of histone H3K27 demethylases inactivates brachyury (TBXT) and promotes chordoma cell death.

  • Read more about Inhibition of histone H3K27 demethylases inactivates brachyury (TBXT) and promotes chordoma cell death.

The SNM1A DNA repair nuclease.

  • Read more about The SNM1A DNA repair nuclease.

Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19.

  • Read more about Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19.

Ten simple rules for open human health research.

  • Read more about Ten simple rules for open human health research.

Atg8-Family Proteins-Structural Features and Molecular Interactions in Autophagy and Beyond

  • Read more about Atg8-Family Proteins-Structural Features and Molecular Interactions in Autophagy and Beyond

Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor.

  • Read more about Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor.

What Are the Odds of Finding a COVID-19 Drug from a Lab Repurposing Screen?

  • Read more about What Are the Odds of Finding a COVID-19 Drug from a Lab Repurposing Screen?

LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium.

  • Read more about LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium.

Nanopore Enzymology to Study Protein Kinases and Their Inhibition by Small Molecules.

  • Read more about Nanopore Enzymology to Study Protein Kinases and Their Inhibition by Small Molecules.

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