Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor. Read more about Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor.
What Are the Odds of Finding a COVID-19 Drug from a Lab Repurposing Screen? Read more about What Are the Odds of Finding a COVID-19 Drug from a Lab Repurposing Screen?
LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium. Read more about LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium.
Nanopore Enzymology to Study Protein Kinases and Their Inhibition by Small Molecules. Read more about Nanopore Enzymology to Study Protein Kinases and Their Inhibition by Small Molecules.
NeuroChat with Research Assistant Professor Alison Axtman. Read more about NeuroChat with Research Assistant Professor Alison Axtman.
Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate. Read more about Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate.
Structural and functional diversity calls for a new classification of ABC transporters. Read more about Structural and functional diversity calls for a new classification of ABC transporters.
PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor. Read more about PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor.
PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase. Read more about PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.
Decoding the Papain Inhibitor from Streptomyces mobaraensis as Being Hydroxylated Chymostatin Derivatives: Purification, Structure Analysis, and Putative Biosynthetic Pathway. Read more about Decoding the Papain Inhibitor from Streptomyces mobaraensis as Being Hydroxylated Chymostatin Derivatives: Purification, Structure Analysis, and Putative Biosynthetic Pathway.
