A novel screening approach comparing kinase activity of small molecule inhibitors with similar molecular structures and distinct biologic effects in triple-negative breast cancer to identify targetable signaling pathways. Read more about A novel screening approach comparing kinase activity of small molecule inhibitors with similar molecular structures and distinct biologic effects in triple-negative breast cancer to identify targetable signaling pathways.
Deliberately Losing Control of C-H Activation Processes in the Design of Small Molecule Fragment Arrays Targeting Peroxisomal Metabolism. Read more about Deliberately Losing Control of C-H Activation Processes in the Design of Small Molecule Fragment Arrays Targeting Peroxisomal Metabolism.
Nucleotide Binding, Evolutionary Insights, and Interaction Partners of the Pseudokinase Unc-51-like Kinase 4. Read more about Nucleotide Binding, Evolutionary Insights, and Interaction Partners of the Pseudokinase Unc-51-like Kinase 4.
Generation and validation of recombinant antibodies to study human aminoacyl tRNA synthetases. Read more about Generation and validation of recombinant antibodies to study human aminoacyl tRNA synthetases.
GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer. Read more about GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer.
Mining Public Domain Data to Develop Selective DYRK1A Inhibitors. Read more about Mining Public Domain Data to Develop Selective DYRK1A Inhibitors.
Inhibition of histone H3K27 demethylases inactivates brachyury (TBXT) and promotes chordoma cell death. Read more about Inhibition of histone H3K27 demethylases inactivates brachyury (TBXT) and promotes chordoma cell death.
Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19. Read more about Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19.
Ten simple rules for open human health research. Read more about Ten simple rules for open human health research.
