PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase. Read more about PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.
Decoding the Papain Inhibitor from Streptomyces mobaraensis as Being Hydroxylated Chymostatin Derivatives: Purification, Structure Analysis, and Putative Biosynthetic Pathway. Read more about Decoding the Papain Inhibitor from Streptomyces mobaraensis as Being Hydroxylated Chymostatin Derivatives: Purification, Structure Analysis, and Putative Biosynthetic Pathway.
Concise, gram-scale synthesis of furo[2,3-b]pyridines with functional handles for chemoselective cross-coupling. Read more about Concise, gram-scale synthesis of furo[2,3-b]pyridines with functional handles for chemoselective cross-coupling.
Translational Control during Mammalian Neocortex Development and Postembryonic Neuronal Function. Read more about Translational Control during Mammalian Neocortex Development and Postembryonic Neuronal Function.
Inhibition of the SUV4-20 H1 histone methyltransferase increases frataxin expression in Friedreich's ataxia patient cells. Read more about Inhibition of the SUV4-20 H1 histone methyltransferase increases frataxin expression in Friedreich's ataxia patient cells.
Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease. Read more about Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease.
Selective targeting of the αC and DFG-out pocket in p38 MAPK. Read more about Selective targeting of the αC and DFG-out pocket in p38 MAPK.
A novel allosteric modulator of the cannabinoid CB1 receptor ameliorates hyperdopaminergia endophenotypes in rodent models. Read more about A novel allosteric modulator of the cannabinoid CB1 receptor ameliorates hyperdopaminergia endophenotypes in rodent models.
Design of new disubstituted imidazo[1,2-b]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation. Read more about Design of new disubstituted imidazo[1,2-b]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation.
Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major. Read more about Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major.
