Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12. Read more about Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12.
Preclinical drug studies in MEN1-related neuroendocrine neoplasms (MEN1-NENs). Read more about Preclinical drug studies in MEN1-related neuroendocrine neoplasms (MEN1-NENs).
Identifying the target of an antiparasitic compound in Toxoplasma using thermal proteome profiling. Read more about Identifying the target of an antiparasitic compound in Toxoplasma using thermal proteome profiling.
Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma. Read more about Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma.
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7. Read more about Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7.
Probing the Plasticity in the Active Site of Protein N-terminal Methyltransferase 1 Using Bisubstrate Analogs. Read more about Probing the Plasticity in the Active Site of Protein N-terminal Methyltransferase 1 Using Bisubstrate Analogs.
Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1. Read more about Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1.
Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases. Read more about Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases.
Potent antiviral activity of novel multi-substituted 4-anilinoquin(az)olines. Read more about Potent antiviral activity of novel multi-substituted 4-anilinoquin(az)olines.
Naturally occurring cobalamin (B12) analogs can function as cofactors for human methylmalonyl-CoA mutase. Read more about Naturally occurring cobalamin (B12) analogs can function as cofactors for human methylmalonyl-CoA mutase.
