Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis. Read more about Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis.
A Single-Stranded DNA-Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks. Read more about A Single-Stranded DNA-Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks.
BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy. Read more about BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy.
Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene. Read more about Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene.
Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking. Read more about Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking.
Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK. Read more about Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK.
Identification of lysine isobutyrylation as a new histone modification mark. Read more about Identification of lysine isobutyrylation as a new histone modification mark.
How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition-The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine. Read more about How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition-The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine.
Human MettL3-MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro. Read more about Human MettL3-MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro.
Molecular basis for ubiquitin ligase CRL2FEM1C-mediated recognition of C-degron. Read more about Molecular basis for ubiquitin ligase CRL2FEM1C-mediated recognition of C-degron.
