Conformational plasticity of the ULK3 kinase domain. Read more about Conformational plasticity of the ULK3 kinase domain.
Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors. Read more about Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors.
NEK5 activity regulates the mesenchymal and migratory phenotype in breast cancer cells. Read more about NEK5 activity regulates the mesenchymal and migratory phenotype in breast cancer cells.
Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors. Read more about Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors.
Integrated analysis of Shank1 PDZ interactions with C-terminal and internal binding motifs. Read more about Integrated analysis of Shank1 PDZ interactions with C-terminal and internal binding motifs.
Rapid and accurate agglutination-based testing for SARS-CoV-2 antibodies. Read more about Rapid and accurate agglutination-based testing for SARS-CoV-2 antibodies.
Opinion: Independent third-party entities as a model for validation of commercial antibodies. Read more about Opinion: Independent third-party entities as a model for validation of commercial antibodies.
Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain. Read more about Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain.
Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma. Read more about Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma.
Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes. Read more about Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes.