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Conformational plasticity of the ULK3 kinase domain.

  • Read more about Conformational plasticity of the ULK3 kinase domain.

Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors.

  • Read more about Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors.

NEK5 activity regulates the mesenchymal and migratory phenotype in breast cancer cells.

  • Read more about NEK5 activity regulates the mesenchymal and migratory phenotype in breast cancer cells.

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors.

  • Read more about Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors.

Integrated analysis of Shank1 PDZ interactions with C-terminal and internal binding motifs.

  • Read more about Integrated analysis of Shank1 PDZ interactions with C-terminal and internal binding motifs.

Rapid and accurate agglutination-based testing for SARS-CoV-2 antibodies.

  • Read more about Rapid and accurate agglutination-based testing for SARS-CoV-2 antibodies.

Opinion: Independent third-party entities as a model for validation of commercial antibodies.

  • Read more about Opinion: Independent third-party entities as a model for validation of commercial antibodies.

Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain.

  • Read more about Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain.

Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma.

  • Read more about Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma.

Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes.

  • Read more about Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes.

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