The structural basis of fatty acid elongation by the ELOVL elongases. Read more about The structural basis of fatty acid elongation by the ELOVL elongases.
Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source. Read more about Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source.
Remodelin Is a Cryptic Assay Interference Chemotype That Does Not Inhibit NAT10-Dependent Cytidine Acetylation. Read more about Remodelin Is a Cryptic Assay Interference Chemotype That Does Not Inhibit NAT10-Dependent Cytidine Acetylation.
The Structure-Based Design of SARS-CoV-2 nsp14 Methyltransferase Ligands Yields Nanomolar Inhibitors. Read more about The Structure-Based Design of SARS-CoV-2 nsp14 Methyltransferase Ligands Yields Nanomolar Inhibitors.
Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput Screening. Read more about Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput Screening.
Development of LM98, a Small-Molecule TEAD Inhibitor Derived from Flufenamic Acid. Read more about Development of LM98, a Small-Molecule TEAD Inhibitor Derived from Flufenamic Acid.
Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19. Read more about Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19.
An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 Mpro inhibitor. Read more about An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 Mpro inhibitor.
Genetic Variability of the SARS-CoV-2 Pocketome. Read more about Genetic Variability of the SARS-CoV-2 Pocketome.
MYC protein interactors in gene transcription and cancer. Read more about MYC protein interactors in gene transcription and cancer.
