Cascade Synthesis of Kinase-Privileged 3-Aminoindazoles via Intramolecular N-N Bond Formation. Read more about Cascade Synthesis of Kinase-Privileged 3-Aminoindazoles via Intramolecular N-N Bond Formation.
LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains. Read more about LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains.
Image-Based Annotation of Chemogenomic Libraries for Phenotypic Screening. Read more about Image-Based Annotation of Chemogenomic Libraries for Phenotypic Screening.
Target 2035 - update on the quest for a probe for every protein. Read more about Target 2035 - update on the quest for a probe for every protein.
Nanobodies as allosteric modulators of Parkinson's disease-associated LRRK2. Read more about Nanobodies as allosteric modulators of Parkinson's disease-associated LRRK2.
Longitudinal assessment of reactivity and affinity profile of anti-Jo1 autoantibodies to distinct HisRS domains and a splice variant in a cohort of patients with myositis and anti-synthetase syndrome. Read more about Longitudinal assessment of reactivity and affinity profile of anti-Jo1 autoantibodies to distinct HisRS domains and a splice variant in a cohort of patients with myositis and anti-synthetase syndrome.
The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase. Read more about The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase.
Resistance to kinase inhibition through shortened target engagement. Read more about Resistance to kinase inhibition through shortened target engagement.
Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog. Read more about Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog.
Stopping pandemics before they start: Lessons learned from SARS-CoV-2. Read more about Stopping pandemics before they start: Lessons learned from SARS-CoV-2.
