Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase. Read more about Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase.
Assessing reversible and irreversible binding effects of kinase covalent inhibitors through ADP-Glo assays. Read more about Assessing reversible and irreversible binding effects of kinase covalent inhibitors through ADP-Glo assays.
Quantitative Methods to Study Protein Arginine Methyltransferase 1-9 Activity in Cells. Read more about Quantitative Methods to Study Protein Arginine Methyltransferase 1-9 Activity in Cells.
Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP and STAMBPL1. Read more about Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP and STAMBPL1.
Structure and Function of Protein Arginine Methyltransferase PRMT7. Read more about Structure and Function of Protein Arginine Methyltransferase PRMT7.
Non-canonical role of Hippo tumor suppressor serine/threonine kinase 3 STK3 in prostate cancer. Read more about Non-canonical role of Hippo tumor suppressor serine/threonine kinase 3 STK3 in prostate cancer.
Discovery of a Potent Dual SLK/STK10 Inhibitor Based on a Maleimide Scaffold. Read more about Discovery of a Potent Dual SLK/STK10 Inhibitor Based on a Maleimide Scaffold.
A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells. Read more about A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells.
Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe. Read more about Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe.
Novel quaternary structures of the human prion protein globular domain. Read more about Novel quaternary structures of the human prion protein globular domain.