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Structural basis for the recognition of the S2, S5-phosphorylated RNA polymerase II CTD by the mRNA anti-terminator protein hSCAF4.

  • Read more about Structural basis for the recognition of the S2, S5-phosphorylated RNA polymerase II CTD by the mRNA anti-terminator protein hSCAF4.

Discovery of Novel BRD4 Ligand Scaffolds by Automated Navigation of the Fragment Chemical Space.

  • Read more about Discovery of Novel BRD4 Ligand Scaffolds by Automated Navigation of the Fragment Chemical Space.

The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Xanthines.

  • Read more about The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Xanthines.

Prediction and Validation of a Protein's Free Energy Surface Using Hydrogen Exchange and (Importantly) Its Denaturant Dependence.

  • Read more about Prediction and Validation of a Protein's Free Energy Surface Using Hydrogen Exchange and (Importantly) Its Denaturant Dependence.

Selective BH3 mimetics synergize with BET inhibition to induce mitochondrial apoptosis in rhabdomyosarcoma cells.

  • Read more about Selective BH3 mimetics synergize with BET inhibition to induce mitochondrial apoptosis in rhabdomyosarcoma cells.

Histone lysine methacrylation is a dynamic post-translational modification regulated by HAT1 and SIRT2.

  • Read more about Histone lysine methacrylation is a dynamic post-translational modification regulated by HAT1 and SIRT2.

TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.

  • Read more about TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.

Design of a Potent TLX Agonist by Rational Fragment Fusion.

  • Read more about Design of a Potent TLX Agonist by Rational Fragment Fusion.

Structural Aspects of LIMK Regulation and Pharmacology.

  • Read more about Structural Aspects of LIMK Regulation and Pharmacology.

Autoantibodies against Four-and-a-Half-LIM Domain 1 (FHL1) in Inflammatory Myopathies: Results from an Australian Single-Center Cohort.

  • Read more about Autoantibodies against Four-and-a-Half-LIM Domain 1 (FHL1) in Inflammatory Myopathies: Results from an Australian Single-Center Cohort.

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