Post-transcriptional and Post-translational Modifications of Primary Cilia: How to Fine Tune Your Neuronal Antenna. Read more about Post-transcriptional and Post-translational Modifications of Primary Cilia: How to Fine Tune Your Neuronal Antenna.
PRMT5 regulates ATF4 transcript splicing and oxidative stress response. Read more about PRMT5 regulates ATF4 transcript splicing and oxidative stress response.
Development of novel urea-based ATM kinase inhibitors with subnanomolar cellular potency and high kinome selectivity. Read more about Development of novel urea-based ATM kinase inhibitors with subnanomolar cellular potency and high kinome selectivity.
Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes. Read more about Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes.
PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade. Read more about PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade.
Validating Small Molecule Chemical Probes for Biological Discovery. Read more about Validating Small Molecule Chemical Probes for Biological Discovery.
Identification of 4-anilino-quin(az)oline as a cell active Protein Kinase Novel 3 (PKN3) inhibitor chemotype. Read more about Identification of 4-anilino-quin(az)oline as a cell active Protein Kinase Novel 3 (PKN3) inhibitor chemotype.
Galaxy workflows for fragment-based virtual screening: a case study on the SARS-CoV-2 main protease. Read more about Galaxy workflows for fragment-based virtual screening: a case study on the SARS-CoV-2 main protease.
SAMPL7 protein-ligand challenge: A community-wide evaluation of computational methods against fragment screening and pose-prediction. Read more about SAMPL7 protein-ligand challenge: A community-wide evaluation of computational methods against fragment screening and pose-prediction.
Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology. Read more about Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology.
