Open Source Antibiotics: Simple Diarylimidazoles Are Potent against Methicillin-Resistant Staphylococcus aureus. Read more about Open Source Antibiotics: Simple Diarylimidazoles Are Potent against Methicillin-Resistant Staphylococcus aureus.
Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications. Read more about Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications.
Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning. Read more about Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning.
An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant. Read more about An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant.
SGC-CLK-1: A chemical probe for the Cdc2-like kinases CLK1, CLK2, and CLK4. Read more about SGC-CLK-1: A chemical probe for the Cdc2-like kinases CLK1, CLK2, and CLK4.
Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures. Read more about Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures.
A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors. Read more about A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors.
Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargeting. Read more about Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargeting.
From cultivation to cancer: formation of N-nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications. Read more about From cultivation to cancer: formation of N-nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications.
Chemical, Biochemical, Cellular, and Physiological Characterization of Leucettinib-21, a Down Syndrome and Alzheimer's Disease Drug Candidate. Read more about Chemical, Biochemical, Cellular, and Physiological Characterization of Leucettinib-21, a Down Syndrome and Alzheimer's Disease Drug Candidate.
