SGC-CLK-1: A chemical probe for the Cdc2-like kinases CLK1, CLK2, and CLK4. Read more about SGC-CLK-1: A chemical probe for the Cdc2-like kinases CLK1, CLK2, and CLK4.
Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures. Read more about Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures.
A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors. Read more about A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors.
Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargeting. Read more about Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargeting.
From cultivation to cancer: formation of N-nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications. Read more about From cultivation to cancer: formation of N-nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications.
Chemical, Biochemical, Cellular, and Physiological Characterization of Leucettinib-21, a Down Syndrome and Alzheimer's Disease Drug Candidate. Read more about Chemical, Biochemical, Cellular, and Physiological Characterization of Leucettinib-21, a Down Syndrome and Alzheimer's Disease Drug Candidate.
Synthesis and Biological Evaluation of 2-Substituted Quinazolin-4(3H)-Ones with Antiproliferative Activities. Read more about Synthesis and Biological Evaluation of 2-Substituted Quinazolin-4(3H)-Ones with Antiproliferative Activities.
Epigenetic vulnerabilities of leukemia harboring inactivating EZH2 mutations. Read more about Epigenetic vulnerabilities of leukemia harboring inactivating EZH2 mutations.
The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition. Read more about The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition.
Identification of high-performing antibodies for Moesin for use in Western Blot, immunoprecipitation, and immunofluorescence. Read more about Identification of high-performing antibodies for Moesin for use in Western Blot, immunoprecipitation, and immunofluorescence.
