Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells. Read more about Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells.
Structural basis for the discriminative recognition of N6-methyladenosine RNA by the human YT521-B homology domain family of proteins. Read more about Structural basis for the discriminative recognition of N6-methyladenosine RNA by the human YT521-B homology domain family of proteins.
The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants. Read more about The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants.
A core of kinase-regulated interactomes defines the neoplastic MDSC lineage. Read more about A core of kinase-regulated interactomes defines the neoplastic MDSC lineage.
Proteomic and biochemical studies of lysine malonylation suggests its malonic aciduria-associated regulatory role in mitochondrial function and fatty acid oxidation. Read more about Proteomic and biochemical studies of lysine malonylation suggests its malonic aciduria-associated regulatory role in mitochondrial function and fatty acid oxidation.
Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors. Read more about Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors.
Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth. Read more about Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth.
Mutations in Known Monogenic High Bone Mass Loci Only Explain a Small Proportion of High Bone Mass cases. Read more about Mutations in Known Monogenic High Bone Mass Loci Only Explain a Small Proportion of High Bone Mass cases.
Overcoming ABCG2-mediated drug resistance with imidazo-[1,2-b]-pyridazine-based Pim1 kinase inhibitors. Read more about Overcoming ABCG2-mediated drug resistance with imidazo-[1,2-b]-pyridazine-based Pim1 kinase inhibitors.
Crystal structure of human nuclear pore complex component NUP43. Read more about Crystal structure of human nuclear pore complex component NUP43.
