Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance. Read more about Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance.
Recent Progress in Histone Demethylase Inhibitors. Read more about Recent Progress in Histone Demethylase Inhibitors.
Use of Methylmalonyl-CoA epimerase in Enhancing Crotonase Stereoselectivity. Read more about Use of Methylmalonyl-CoA epimerase in Enhancing Crotonase Stereoselectivity.
Structure-based identification of inhibitory fragments targeting the p300/CBP-associated factor bromodomain. Read more about Structure-based identification of inhibitory fragments targeting the p300/CBP-associated factor bromodomain.
Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins. Read more about Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins.
8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. Read more about 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors.
Role of reverse phenotyping in interpretation of next generation sequencing data and a review of INPP5E related disorders. Read more about Role of reverse phenotyping in interpretation of next generation sequencing data and a review of INPP5E related disorders.
Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target. Read more about Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential therapeutic target.
Open Access Could Transform Drug Discovery: A Case Study of JQ1. Read more about Open Access Could Transform Drug Discovery: A Case Study of JQ1.
Accurate calculation of the absolute free energy of binding for drug molecules. Read more about Accurate calculation of the absolute free energy of binding for drug molecules.
