Open innovation in neuroscience research and drug discovery. Read more about Open innovation in neuroscience research and drug discovery.
A Highly Selective Chemical Probe for Activin Receptor-like Kinases ALK4 and ALK5. Read more about A Highly Selective Chemical Probe for Activin Receptor-like Kinases ALK4 and ALK5.
SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K. Read more about SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K.
Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design. Read more about Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design.
Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex. Read more about Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex.
The RESOLUTE consortium: unlocking SLC transporters for drug discovery. Read more about The RESOLUTE consortium: unlocking SLC transporters for drug discovery.
New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I-Interacting Kinase (TNNi3K). Read more about New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I-Interacting Kinase (TNNi3K).
Importance of Quantifying Drug-Target Engagement in Cells. Read more about Importance of Quantifying Drug-Target Engagement in Cells.
Crystal structure of DRIK1, a stress-responsive receptor-like pseudokinase, reveals the molecular basis for the absence of ATP binding. Read more about Crystal structure of DRIK1, a stress-responsive receptor-like pseudokinase, reveals the molecular basis for the absence of ATP binding.
Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment. Read more about Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment.