Structure-guided fragment-based drug discovery at the synchrotron: screening binding sites and correlations with hotspot mapping. Read more about Structure-guided fragment-based drug discovery at the synchrotron: screening binding sites and correlations with hotspot mapping.
A Perspective on Extreme Open Science: Companies Sharing Compounds without Restriction. Read more about A Perspective on Extreme Open Science: Companies Sharing Compounds without Restriction.
Structure and function of eTudor domain containing TDRD proteins. Read more about Structure and function of eTudor domain containing TDRD proteins.
Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins. Read more about Crosstalk between RNA Pol II C-Terminal Domain Acetylation and Phosphorylation via RPRD Proteins.
Rapid covalent-probe discovery by electrophile-fragment screening. Read more about Rapid covalent-probe discovery by electrophile-fragment screening.
The dynamic conformational landscape of the protein methyltransferase SETD8. Read more about The dynamic conformational landscape of the protein methyltransferase SETD8.
ALK2 inhibitors display beneficial effects in preclinical models of ACVR1 mutant diffuse intrinsic pontine glioma. Read more about ALK2 inhibitors display beneficial effects in preclinical models of ACVR1 mutant diffuse intrinsic pontine glioma.
Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism. Read more about Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism.
Targeting protein methylation: from chemical tools to precision medicines. Read more about Targeting protein methylation: from chemical tools to precision medicines.
Increased EZH2 expression in prostate cancer is associated with metastatic recurrence following external beam radiotherapy. Read more about Increased EZH2 expression in prostate cancer is associated with metastatic recurrence following external beam radiotherapy.
