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Open innovation in neuroscience research and drug discovery.

  • Read more about Open innovation in neuroscience research and drug discovery.

A Highly Selective Chemical Probe for Activin Receptor-like Kinases ALK4 and ALK5.

  • Read more about A Highly Selective Chemical Probe for Activin Receptor-like Kinases ALK4 and ALK5.

SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K.

  • Read more about SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K.

Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design.

  • Read more about Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design.

Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex.

  • Read more about Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex.

The RESOLUTE consortium: unlocking SLC transporters for drug discovery.

  • Read more about The RESOLUTE consortium: unlocking SLC transporters for drug discovery.

New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I-Interacting Kinase (TNNi3K).

  • Read more about New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I-Interacting Kinase (TNNi3K).

Importance of Quantifying Drug-Target Engagement in Cells.

  • Read more about Importance of Quantifying Drug-Target Engagement in Cells.

Crystal structure of DRIK1, a stress-responsive receptor-like pseudokinase, reveals the molecular basis for the absence of ATP binding.

  • Read more about Crystal structure of DRIK1, a stress-responsive receptor-like pseudokinase, reveals the molecular basis for the absence of ATP binding.

Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment.

  • Read more about Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment.

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