Quantifying CDK inhibitor selectivity in live cells. Read more about Quantifying CDK inhibitor selectivity in live cells.
Human aminolevulinate synthase structure reveals a eukaryotic-specific autoinhibitory loop regulating substrate binding and product release. Read more about Human aminolevulinate synthase structure reveals a eukaryotic-specific autoinhibitory loop regulating substrate binding and product release.
A lower X-gate in TASK channels traps inhibitors within the vestibule. Read more about A lower X-gate in TASK channels traps inhibitors within the vestibule.
Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold. Read more about Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold.
Recognition of nonproline N-terminal residues by the Pro/N-degron pathway. Read more about Recognition of nonproline N-terminal residues by the Pro/N-degron pathway.
Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution. Read more about Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution.
Backbone resonance assignments of the catalytic and regulatory domains of Ca2+/calmodulin-dependent protein kinase 1D. Read more about Backbone resonance assignments of the catalytic and regulatory domains of Ca2+/calmodulin-dependent protein kinase 1D.
Epigenetic switch-induced viral mimicry evasion in chemotherapy resistant breast cancer. Read more about Epigenetic switch-induced viral mimicry evasion in chemotherapy resistant breast cancer.
Crowdsourcing drug discovery for pandemics. Read more about Crowdsourcing drug discovery for pandemics.
Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12. Read more about Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12.
