CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model. Read more about CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model.
L-thyroxin and the non-classical thyroid hormone TETRAC are potent activators of PPARγ. Read more about L-thyroxin and the non-classical thyroid hormone TETRAC are potent activators of PPARγ.
Therapeutic targeting of p300/CBP HAT domain for the treatment of NUT midline carcinoma. Read more about Therapeutic targeting of p300/CBP HAT domain for the treatment of NUT midline carcinoma.
Discovery of a First-in-class Protein Arginine Methyltransferase 6 (PRMT6) Covalent Inhibitor. Read more about Discovery of a First-in-class Protein Arginine Methyltransferase 6 (PRMT6) Covalent Inhibitor.
Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma. Read more about Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma.
GGPS1 Mutations Cause Muscular Dystrophy/Hearing Loss/Ovarian Insufficiency Syndrome. Read more about GGPS1 Mutations Cause Muscular Dystrophy/Hearing Loss/Ovarian Insufficiency Syndrome.
Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response. Read more about Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response.
Radiolabeled cCPE Peptides for SPECT Imaging of Claudin-4 Overexpression in Pancreatic Cancer. Read more about Radiolabeled cCPE Peptides for SPECT Imaging of Claudin-4 Overexpression in Pancreatic Cancer.
Discovery of highly selective inhibitors of calmodulin-dependent kinases that restore insulin sensitivity in the diet-induced obese in vivo mouse model. Read more about Discovery of highly selective inhibitors of calmodulin-dependent kinases that restore insulin sensitivity in the diet-induced obese in vivo mouse model.
Mitochondrial uncoupling protein-dependent signaling in plant bioenergetics and stress response. Read more about Mitochondrial uncoupling protein-dependent signaling in plant bioenergetics and stress response.
