Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK). Read more about Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK).
A fast iterative synthetic approach towards the identification of novel highly selective p38 MAP kinase inhibitors. Read more about A fast iterative synthetic approach towards the identification of novel highly selective p38 MAP kinase inhibitors.
Binding and structural analyses of potent inhibitors of the human Ca2+/calmodulin dependent protein kinase kinase 2 (CAMKK2) identified from a collection of commercially-available kinase inhibitors. Read more about Binding and structural analyses of potent inhibitors of the human Ca2+/calmodulin dependent protein kinase kinase 2 (CAMKK2) identified from a collection of commercially-available kinase inhibitors.
Emerging tools to investigate bromodomain functions. Read more about Emerging tools to investigate bromodomain functions.
An epigenetic screening determines BET proteins as targets to suppress self-renewal and tumorigenicity in canine mammary cancer cells. Read more about An epigenetic screening determines BET proteins as targets to suppress self-renewal and tumorigenicity in canine mammary cancer cells.
Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva-Derived Endothelial Cells. Read more about Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva-Derived Endothelial Cells.
The fungal metabolite chaetocin is a sensitizer for pro-apoptotic therapies in glioblastoma. Read more about The fungal metabolite chaetocin is a sensitizer for pro-apoptotic therapies in glioblastoma.
Janus kinase inhibition for autoinflammation in DNASE2 deficiency. Read more about Janus kinase inhibition for autoinflammation in DNASE2 deficiency.
Synthetic Peptides as Therapeutic Agents: Lessons Learned From Evolutionary Ancient Peptides and Their Transit Across Blood-Brain Barriers. Read more about Synthetic Peptides as Therapeutic Agents: Lessons Learned From Evolutionary Ancient Peptides and Their Transit Across Blood-Brain Barriers.
Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension. Read more about Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension.
