Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1). Read more about Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1).
CDK16: the pick of the understudied PCTAIRE kinases. Read more about CDK16: the pick of the understudied PCTAIRE kinases.
High-Throughput Purification of Protein Kinases from Escherichia coli and Insect Cells. Read more about High-Throughput Purification of Protein Kinases from Escherichia coli and Insect Cells.
High-Throughput Site-Directed Mutagenesis. Read more about High-Throughput Site-Directed Mutagenesis.
Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase. Read more about Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase.
Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3. Read more about Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3.
A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Read more about A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.
Lesson from a Fab-enabled co-crystallization study of TDRD2 and PIWIL1. Read more about Lesson from a Fab-enabled co-crystallization study of TDRD2 and PIWIL1.
Gram-scale synthesis of FICZ, a photoreactive endogenous ligand of the aryl hydrocarbon receptor. Read more about Gram-scale synthesis of FICZ, a photoreactive endogenous ligand of the aryl hydrocarbon receptor.
