LOTUS domain is a novel class of G-rich and G-quadruplex RNA binding domain. Read more about LOTUS domain is a novel class of G-rich and G-quadruplex RNA binding domain.
Comparative structural analyses and nucleotide-binding characterization of the four KH domains of FUBP1. Read more about Comparative structural analyses and nucleotide-binding characterization of the four KH domains of FUBP1.
Catalytic Domain Plasticity of MKK7 Reveals Structural Mechanisms of Allosteric Activation and Diverse Targeting Opportunities. Read more about Catalytic Domain Plasticity of MKK7 Reveals Structural Mechanisms of Allosteric Activation and Diverse Targeting Opportunities.
DFG-1 residue controls inhibitor binding mode and affinity providing a basis for rational design of kinase inhibitor selectivity. Read more about DFG-1 residue controls inhibitor binding mode and affinity providing a basis for rational design of kinase inhibitor selectivity.
Leveraging an Open Science Drug Discovery Model to Develop CNS Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma. Read more about Leveraging an Open Science Drug Discovery Model to Develop CNS Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma.
A novel screening approach comparing kinase activity of small molecule inhibitors with similar molecular structures and distinct biologic effects in triple-negative breast cancer to identify targetable signaling pathways. Read more about A novel screening approach comparing kinase activity of small molecule inhibitors with similar molecular structures and distinct biologic effects in triple-negative breast cancer to identify targetable signaling pathways.
Deliberately Losing Control of C-H Activation Processes in the Design of Small Molecule Fragment Arrays Targeting Peroxisomal Metabolism. Read more about Deliberately Losing Control of C-H Activation Processes in the Design of Small Molecule Fragment Arrays Targeting Peroxisomal Metabolism.
Nucleotide Binding, Evolutionary Insights, and Interaction Partners of the Pseudokinase Unc-51-like Kinase 4. Read more about Nucleotide Binding, Evolutionary Insights, and Interaction Partners of the Pseudokinase Unc-51-like Kinase 4.
Generation and validation of recombinant antibodies to study human aminoacyl tRNA synthetases. Read more about Generation and validation of recombinant antibodies to study human aminoacyl tRNA synthetases.
GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer. Read more about GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer.
