BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation. Read more about BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation.
Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications. Read more about Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications.
C81-evoked inhibition of the TNFR1-NFκB pathway during inflammatory processes for stabilization of the impaired vascular endothelial barrier for leukocytes. Read more about C81-evoked inhibition of the TNFR1-NFκB pathway during inflammatory processes for stabilization of the impaired vascular endothelial barrier for leukocytes.
Exploring protein hotspots by optimized fragment pharmacophores. Read more about Exploring protein hotspots by optimized fragment pharmacophores.
Towards a RIOK2 chemical probe: cellular potency improvement of a selective 2-(acylamino)pyridine series. Read more about Towards a RIOK2 chemical probe: cellular potency improvement of a selective 2-(acylamino)pyridine series.
Synthetic Opportunities and Challenges for Macrocyclic Kinase Inhibitors. Read more about Synthetic Opportunities and Challenges for Macrocyclic Kinase Inhibitors.
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction. Read more about Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction.
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression. Read more about Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression.
Epitope-specific antibody responses differentiate COVID-19 outcomes and variants of concern. Read more about Epitope-specific antibody responses differentiate COVID-19 outcomes and variants of concern.
Controlling the Covalent Reactivity of a Kinase Inhibitor with Light. Read more about Controlling the Covalent Reactivity of a Kinase Inhibitor with Light.
