Structural Insights into Plasticity and Discovery of Remdesivir Metabolite GS-441524 Binding in SARS-CoV-2 Macrodomain. Read more about Structural Insights into Plasticity and Discovery of Remdesivir Metabolite GS-441524 Binding in SARS-CoV-2 Macrodomain.
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Read more about Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.
Hepatitis B virus resistance to tenofovir: fact or fiction? A systematic literature review and structural analysis of drug resistance mechanisms. Read more about Hepatitis B virus resistance to tenofovir: fact or fiction? A systematic literature review and structural analysis of drug resistance mechanisms.
A High-Throughput Radioactivity-Based Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex. Read more about A High-Throughput Radioactivity-Based Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex.
Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy. Read more about Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy.
Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders. Read more about Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders.
Endogenous vitamin E metabolites mediate allosteric PPARγ activation with unprecedented co-regulatory interactions. Read more about Endogenous vitamin E metabolites mediate allosteric PPARγ activation with unprecedented co-regulatory interactions.
Editorial: Structural Studies of Protein Complexes in Signaling Pathways. Read more about Editorial: Structural Studies of Protein Complexes in Signaling Pathways.
Identifying and Validating MYC:Protein Interactors in Pursuit of Novel Anti-MYC Therapies. Read more about Identifying and Validating MYC:Protein Interactors in Pursuit of Novel Anti-MYC Therapies.
Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters. Read more about Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.
