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Endogenous vitamin E metabolites mediate allosteric PPARγ activation with unprecedented co-regulatory interactions.

  • Read more about Endogenous vitamin E metabolites mediate allosteric PPARγ activation with unprecedented co-regulatory interactions.

Editorial: Structural Studies of Protein Complexes in Signaling Pathways.

  • Read more about Editorial: Structural Studies of Protein Complexes in Signaling Pathways.

Identifying and Validating MYC:Protein Interactors in Pursuit of Novel Anti-MYC Therapies.

  • Read more about Identifying and Validating MYC:Protein Interactors in Pursuit of Novel Anti-MYC Therapies.

Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.

  • Read more about Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.

BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation.

  • Read more about BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation.

Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications.

  • Read more about Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications.

C81-evoked inhibition of the TNFR1-NFκB pathway during inflammatory processes for stabilization of the impaired vascular endothelial barrier for leukocytes.

  • Read more about C81-evoked inhibition of the TNFR1-NFκB pathway during inflammatory processes for stabilization of the impaired vascular endothelial barrier for leukocytes.

Exploring protein hotspots by optimized fragment pharmacophores.

  • Read more about Exploring protein hotspots by optimized fragment pharmacophores.

Towards a RIOK2 chemical probe: cellular potency improvement of a selective 2-(acylamino)pyridine series.

  • Read more about Towards a RIOK2 chemical probe: cellular potency improvement of a selective 2-(acylamino)pyridine series.

Synthetic Opportunities and Challenges for Macrocyclic Kinase Inhibitors.

  • Read more about Synthetic Opportunities and Challenges for Macrocyclic Kinase Inhibitors.

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