Endogenous vitamin E metabolites mediate allosteric PPARγ activation with unprecedented co-regulatory interactions. Read more about Endogenous vitamin E metabolites mediate allosteric PPARγ activation with unprecedented co-regulatory interactions.
Editorial: Structural Studies of Protein Complexes in Signaling Pathways. Read more about Editorial: Structural Studies of Protein Complexes in Signaling Pathways.
Identifying and Validating MYC:Protein Interactors in Pursuit of Novel Anti-MYC Therapies. Read more about Identifying and Validating MYC:Protein Interactors in Pursuit of Novel Anti-MYC Therapies.
Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters. Read more about Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters.
BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation. Read more about BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation.
Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications. Read more about Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications.
C81-evoked inhibition of the TNFR1-NFκB pathway during inflammatory processes for stabilization of the impaired vascular endothelial barrier for leukocytes. Read more about C81-evoked inhibition of the TNFR1-NFκB pathway during inflammatory processes for stabilization of the impaired vascular endothelial barrier for leukocytes.
Exploring protein hotspots by optimized fragment pharmacophores. Read more about Exploring protein hotspots by optimized fragment pharmacophores.
Towards a RIOK2 chemical probe: cellular potency improvement of a selective 2-(acylamino)pyridine series. Read more about Towards a RIOK2 chemical probe: cellular potency improvement of a selective 2-(acylamino)pyridine series.
Synthetic Opportunities and Challenges for Macrocyclic Kinase Inhibitors. Read more about Synthetic Opportunities and Challenges for Macrocyclic Kinase Inhibitors.