MSC-1186, a Highly Selective Pan-SRPK Inhibitor Based on an Exceptionally Decorated Benzimidazole-Pyrimidine Core. Read more about MSC-1186, a Highly Selective Pan-SRPK Inhibitor Based on an Exceptionally Decorated Benzimidazole-Pyrimidine Core.
Skeletal muscle metabolism and contraction performance regulation by teneurin C-terminal-associated peptide-1. Read more about Skeletal muscle metabolism and contraction performance regulation by teneurin C-terminal-associated peptide-1.
The future of chemical probes is diversity. Read more about The future of chemical probes is diversity.
Development of a Potent Cyclic Peptide Inhibitor of the nNOS/PSD-95 Interaction. Read more about Development of a Potent Cyclic Peptide Inhibitor of the nNOS/PSD-95 Interaction.
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence. Read more about Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence.
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Read more about Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2.
Detection of antibodies against the huntingtin protein in human plasma. Read more about Detection of antibodies against the huntingtin protein in human plasma.
SGC-CAMKK2-1: A Chemical Probe for CAMKK2. Read more about SGC-CAMKK2-1: A Chemical Probe for CAMKK2.
Generative and reinforcement learning approaches for the automated de novo design of bioactive compounds. Read more about Generative and reinforcement learning approaches for the automated de novo design of bioactive compounds.
Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures. Read more about Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures.
