PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade. Read more about PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade.
Validating Small Molecule Chemical Probes for Biological Discovery. Read more about Validating Small Molecule Chemical Probes for Biological Discovery.
Identification of 4-anilino-quin(az)oline as a cell active Protein Kinase Novel 3 (PKN3) inhibitor chemotype. Read more about Identification of 4-anilino-quin(az)oline as a cell active Protein Kinase Novel 3 (PKN3) inhibitor chemotype.
Galaxy workflows for fragment-based virtual screening: a case study on the SARS-CoV-2 main protease. Read more about Galaxy workflows for fragment-based virtual screening: a case study on the SARS-CoV-2 main protease.
SAMPL7 protein-ligand challenge: A community-wide evaluation of computational methods against fragment screening and pose-prediction. Read more about SAMPL7 protein-ligand challenge: A community-wide evaluation of computational methods against fragment screening and pose-prediction.
Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology. Read more about Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology.
Synthesis and biological evaluation of Haspin inhibitors: Kinase inhibitory potency and cellular activity. Read more about Synthesis and biological evaluation of Haspin inhibitors: Kinase inhibitory potency and cellular activity.
A Consensus Compound/Bioactivity Dataset for Data-Driven Drug Design and Chemogenomics. Read more about A Consensus Compound/Bioactivity Dataset for Data-Driven Drug Design and Chemogenomics.
AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery. Read more about AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery.