A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells. Read more about A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells.
Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe. Read more about Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe.
Novel quaternary structures of the human prion protein globular domain. Read more about Novel quaternary structures of the human prion protein globular domain.
Design and Development of a Chemical Probe for Pseudokinase Ca2+/calmodulin-Dependent Ser/Thr Kinase. Read more about Design and Development of a Chemical Probe for Pseudokinase Ca2+/calmodulin-Dependent Ser/Thr Kinase.
Characterizing the role of the dark kinome in neurodegenerative disease - A mini review. Read more about Characterizing the role of the dark kinome in neurodegenerative disease - A mini review.
Single tracer-based protocol for broad-spectrum kinase profiling in live cells with NanoBRET. Read more about Single tracer-based protocol for broad-spectrum kinase profiling in live cells with NanoBRET.
Synthesis and Evaluation of Novel 1,2,6-Thiadiazinone Kinase Inhibitors as Potent Inhibitors of Solid Tumors. Read more about Synthesis and Evaluation of Novel 1,2,6-Thiadiazinone Kinase Inhibitors as Potent Inhibitors of Solid Tumors.
Structure-Activity Relationship of USP5 Inhibitors. Read more about Structure-Activity Relationship of USP5 Inhibitors.
The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif. Read more about The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif.
Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells. Read more about Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells.
