Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress. Read more about Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress.
Development of Selective Pyrido[2,3-d]pyrimidin-7(8H)-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors. Read more about Development of Selective Pyrido[2,3-d]pyrimidin-7(8H)-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors.
Identification of high-performing antibodies for Vacuolar protein sorting-associated protein 35 (hVPS35) for use in Western Blot, immunoprecipitation and immunofluorescence. Read more about Identification of high-performing antibodies for Vacuolar protein sorting-associated protein 35 (hVPS35) for use in Western Blot, immunoprecipitation and immunofluorescence.
Big data and benchmarking initiatives to bridge the gap from AlphaFold to drug design. Read more about Big data and benchmarking initiatives to bridge the gap from AlphaFold to drug design.
Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator. Read more about Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator.
Structure-guided drug discovery: back to the future. Read more about Structure-guided drug discovery: back to the future.
Discovery of Conformationally Constrained ALK2 Inhibitors. Read more about Discovery of Conformationally Constrained ALK2 Inhibitors.
Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex. Read more about Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex.
Illumination of understudied ciliary kinases. Read more about Illumination of understudied ciliary kinases.
Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor. Read more about Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor.
