A Concerted Action of UBA5 C-Terminal Unstructured Regions Is Important for Transfer of Activated UFM1 to UFC1. Read more about A Concerted Action of UBA5 C-Terminal Unstructured Regions Is Important for Transfer of Activated UFM1 to UFC1.
Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family. Read more about Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family.
Identification of Pyrimidine-Based Lead Compounds for Understudied Kinases Implicated in Driving Neurodegeneration. Read more about Identification of Pyrimidine-Based Lead Compounds for Understudied Kinases Implicated in Driving Neurodegeneration.
High-Throughput Crystallography Reveals Boron-Containing Inhibitors of a Penicillin-Binding Protein with Di- and Tricovalent Binding Modes. Read more about High-Throughput Crystallography Reveals Boron-Containing Inhibitors of a Penicillin-Binding Protein with Di- and Tricovalent Binding Modes.
Production of Recombinant PRMT Proteins using the Baculovirus Expression Vector System. Read more about Production of Recombinant PRMT Proteins using the Baculovirus Expression Vector System.
Discovery and Characterization of Selective and Ligand-Efficient DYRK Inhibitors. Read more about Discovery and Characterization of Selective and Ligand-Efficient DYRK Inhibitors.
Trends in kinase drug discovery: targets, indications and inhibitor design. Read more about Trends in kinase drug discovery: targets, indications and inhibitor design.
The Small-Molecule Inhibitor MRIA9 Reveals Novel Insights into the Cell Cycle Roles of SIK2 in Ovarian Cancer Cells. Read more about The Small-Molecule Inhibitor MRIA9 Reveals Novel Insights into the Cell Cycle Roles of SIK2 in Ovarian Cancer Cells.
Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase. Read more about Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase.
