Identification and Utilization of a Chemical Probe to Interrogate the Roles of PIKfyve in the Lifecycle of β-Coronaviruses. Read more about Identification and Utilization of a Chemical Probe to Interrogate the Roles of PIKfyve in the Lifecycle of β-Coronaviruses.
A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Read more about A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.
Development and Characterization of Type I, Type II, and Type III LIM-Kinase Chemical Probes. Read more about Development and Characterization of Type I, Type II, and Type III LIM-Kinase Chemical Probes.
Fragment-based discovery of orphan nuclear receptor Nur77/NGFI-B ligands. Read more about Fragment-based discovery of orphan nuclear receptor Nur77/NGFI-B ligands.
ChemBioPort: an online portal to navigate the structure, function and chemical inhibition of the human proteome. Read more about ChemBioPort: an online portal to navigate the structure, function and chemical inhibition of the human proteome.
Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial PfGSK3/PfPK6 with Activity against Blood Stage Parasites In Vitro. Read more about Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial PfGSK3/PfPK6 with Activity against Blood Stage Parasites In Vitro.
Covalent Modification of Bromodomain Proteins by Peptides Containing a DNA Damage-Induced, Histone Post-Translational Modification. Read more about Covalent Modification of Bromodomain Proteins by Peptides Containing a DNA Damage-Induced, Histone Post-Translational Modification.
Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation. Read more about Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation.
De novo design of immunoglobulin-like domains. Read more about De novo design of immunoglobulin-like domains.
A Screening of Epigenetic Therapeutic Targets for Non-Small Cell Lung Cancer Reveals PADI4 and KDM6B as Promising Candidates. Read more about A Screening of Epigenetic Therapeutic Targets for Non-Small Cell Lung Cancer Reveals PADI4 and KDM6B as Promising Candidates.
